Pandemic Action Network Statement on a New World Bank Fund for Pandemic Prevention, Preparedness, and Response

Statement by Pandemic Action Network Co-Founder Carolyn Reynolds on the decision by the World Bank’s Board of Executive Directors to establish a new Financial Intermediary Fund for Pandemic Prevention, Preparedness, and Response: 

“Today’s decision by the World Bank’s Board of Executive Directors to establish a new global pandemic fund is an important step forward to heed the hard lessons of COVID-19 and make the world safer from pandemics. The fund offers the potential to marshal significant new financing to help prevent such a deadly and costly crisis from happening again. As the fund moves from concept to reality, global leaders should seize this opportunity to ensure it is catalytic, inclusive, and accountable. 

“The COVID crisis has shown us that pandemic prevention and preparedness is in everyone’s interest, and it should be everyone’s business. The US$1.1 billion pledged to the fund thus far is still a fraction of the estimated US$10 billion annually that global health and finance experts agree is urgently needed to bolster the world’s pandemic defenses. We urge more governments, philanthropies, and other funders to seize this moment to pandemic proof our collective future by stepping up and investing in this new fund.” 

Launching a New Pandemic Preparedness Fund: A Crack in the Cycle of Panic and Neglect?

Read the full analysis here on csis.org.

We are in a fragile, yet promising moment when it comes to heeding the lessons of the COVID-19 crisis. But a chance to begin to break the cycle of crisis and complacency and strengthen global security is finally within our reach, with the emergence of an international coalition to increase financing for pandemic preparedness. A new CSIS commentary from Carolyn Reynolds and J. Stephen Morrison discusses how the creation of a new Pandemic Preparedness Fund offers a near-term opportunity to mobilize significant new investments that are unlikely to happen otherwise, by using catalytic grant financing to close critical gaps in preparedness. Pivotal decisions remain to ensure that the fund has clearly defined strategic priorities that advance shared security interests; expands the pool of funding available for pandemic preparedness and response by tapping creative additional sources beyond official development assistance; and is steered by a decisive governing body. Strong U.S. leadership and financial commitment, bridging the U.S. administration and Congress, and resting on a durable bipartisan consensus, will be the single most important factor in moving the fund from its infancy into an instrument with the long-term vision, clear and unique purpose, and legitimacy to deliver rapid and sustainable results. Just as the United States led the world two decades ago to launch PEPFAR and the Global Fund to combat the global AIDS crisis, the United States should now lead and rally the world to launch this new fund and help prevent the next pandemic.

Read the full analysis here on csis.org.

Falling Short: Pandemic Action Network Statement on the 2022 G7 Leaders’ Summit

G7 Leaders fell far short of what is needed to finish the job on COVID-19 and prevent the next pandemic. Leaders are facing compounding and intertwined crises, but this is no time to deprioritize health security, which is fundamental to addressing virtually every other crisis facing humanity. This year’s G7 Leaders’ Summit represents a missed opportunity to take decisive action and fundamentally shift the G7’s record on pandemic preparedness and response.   Instead, we saw more of the “same strategy but different day” cycle of rearranging recommendations and commitments.

On finance, G7 Leaders collectively failed to deliver adequate financing to fund the provision of tests and treatments and delivery of vaccines still needed in low- and middle-income countries (LMICs). While we are pleased that the U.K. joined other G7 countries by pledging funding for the emerging global Pandemic Prevention, Preparedness and Response fund at the World Bank, we need to hear that founding partners are committed to an inclusive, representative future fund which will include LMICs, communities, and civil society in its governance from the outset as well as equity in its decision-making. Overall, we need to see a commitment to investing in these ongoing priorities by growing the global pool of funding available for pandemic preparedness and response.

On governance, leaders also missed an opportunity to elevate leadership on pandemic preparedness and response by endorsing the creation of a Global Health Threats Council — as proposed by the Independent Panel for Pandemic Preparedness and Response — and laying the groundwork for a broader coalition of countries and leaders. A political mechanism of this kind is essential to sustain action and investment across countries and advance ambitious proposals, such as those described in the G7’s Pact for Pandemic Readiness

As the G7 focuses on the world’s stability with commitments on climate and food security, proactively preparing for pandemics must be a part of that mix. These existential threats are interconnected. Accelerating climate change means the world is more likely to experience future outbreaks with more regularity. Whether such outbreaks become pandemics or can be quashed in time hinges on the political choices leaders are making right now. And today, the G7 chose complacency and stagnation over progress when it comes to pandemic preparedness.

We urge the G7 to take forward the Pact for Pandemic Readiness and turn it into action with urgency in the remaining six months of this year and beyond. The COVID crisis has laid bare the costs of inaction. We cannot afford to move on without learning the lessons over the last two years — particularly for the most vulnerable and LMIC populations, many of whom still lack access to lifesaving tests, treatments and vaccines. 

The current and future G7 presidencies of Germany and Japan must prioritize getting bold pandemic preparedness and COVID-19 response action back on track as a key part of addressing the world’s interlocking crises — they simply cannot afford not to. Click To Tweet

What To Know Before the G7 Leaders’ Summit

The G7 Leaders’ Summit is just around the corner, and — as one of the five priorities of the German Presidency — pandemic preparedness and response is expected to have a central role in the meeting. In Germany’s own words, this year’s program aims “to expand the G7’s pioneering role in the commitment to pandemic prevention and control as well as improving the international health architecture.” While this might be a good omen for relevant agreements and commitments, the G7’s record on pandemics is not consistent and makes many of us wary. So, what do we need to know to understand the landscape and ensure this G7 goes beyond a series of photo ops and warm words?

A bit of historical background… Seven years ago, under the German Presidency as well, the Ebola outbreak in West Africa drove forward similar promises to those on the table in 2022. The 2015 Elmau Declaration contained crucial commitments, including support for the “World Bank to develop a Pandemic Emergency Facility” advanced by the G20 and strengthening of a mechanism for rapid response to pandemics. Side note, the 2015 declaration also includes clear language on “finding a solution to the conflict in Ukraine.” Déjà vu, anyone? We know that over the following years, these commitments lost traction and their implementation lagged. The following declarations — 2016 Ise Shima Declaration, 2017 Taormina Declaration, 2018 Charlevoix Declaration, and the 2019 Biarritz Declaration — progressively erased pandemics off the agenda until it made it back in 2020, this time under an unprecedented global crisis.   

So, what tells us that 2022 could be different? Germany’s G7 leadership this year is a reason for optimism. The country has made significant contributions to the ACT-Accelerator, has supported and raised funds for the COVAX Advance Market Commitment mechanism, and also committed financial contributions to CEPI and the forthcoming new Pandemic Prevention, Preparedness, and Response Fund at the World Bank. Moreover, in preparation for the Summit, Germany has convened high-level officials to discuss pandemics and pave the way for the Leaders’ Summit.

The G7’s preparatory work in May provides some hints and insights about what agreements might be in the making. Here’s a summary of the outcomes and work of the following Ministers’ meetings:

  • Foreign Ministers. They have mainly focused on the G7’s response to the COVID-19 pandemic and on addressing gaps in the global vaccination campaign. On May 13, they released an “Action Plan on COVID-19,” which aims to align the group’s response efforts. In its last communiqué, they also noted that they are already working on “planning the ongoing COVID-19 response for 2023” but didn’t share specific details.
  • Health Ministers. Their last communiqué provides an overview of the issues and variables shaping the conversation and shows how the G7 is looking into preventing future pandemics and enhancing the world’s response to pandemic threats. Recently they released a concept note for a “G7 Pact for Pandemic Readiness,” which has a strong emphasis on surveillance. It is unclear though if other essential aspects for pandemic preparedness will also be considered by the group and how.  
  • Finance Ministers and Central Bank Governors. As they are responsible for aligning commitments and funding, their last communiqué helps to understand what are the competing priorities. They expressed support for the establishment of the new Pandemic Prevention, Preparedness, and Response Fund, hosted by the World Bank, but they clearly stated that a broader group of countries should contribute financially as well. 
  • Development Ministers. This group has discussed the effects of COVID-19, as shown in their last communiqué, and has worked with Health Ministers to accelerate the G7’s response to ending the pandemic globally — putting emphasis on access to vaccines, diagnostics, and therapeutics — and increasing countries’ capacities on pandemic preparedness and response. It stands out that their support for expanding access to vaccines, testing, and therapeutics worldwide seems to rely only on voluntary technology transfer and not in more proactive measures. 

What’s missing, and what’s ahead? If after reviewing these different pieces you get a feeling that something is missing, you are not alone. So far, the information proactively disclosed by the German Presidency does not reveal specific actions or preliminary plans. It remains unclear how most of the commitments will be advanced and turn into concrete changes. With the information available up to this point, this next G7 Leaders’ Summit could yield good commitments but the risk of forgetting them in the coming years might be as present as in 2015. As such, the six months following the Leaders’ Summit will be critical to ensuring clear actions and setting the stage for Japan to pick up the G7 leadership baton in 2023.

If you are attending the G7, please let us know! Otherwise, stay in touch on social media.

Shifting the G7’s Record on Pandemics

Something has to change when it comes to global leaders’ response to pandemics. The concern used to be that panic-induced action at the outset of a pandemic turns quickly to neglect once the emergency is over. But COVID-19 brought a new additional concern: the cycle switched to “neglect” while still battling the crisis phase of the pandemic. 

The G7’s own record on pandemics shows the same pattern of panic and neglect. In 2015 — also under the German Presidency — the Ebola epidemic in West Africa brought a long list of commitments that echoes what should have been done to prevent the current crisis: assisting countries in implementing the International Health Regulations, making financing for response and preparedness immediately available, improving WHO’s capabilities, and setting up surveillance networks. Yet, these commitments failed to translate into tangible and sustained action. The devastating experience of the COVID-19 pandemic leaves no doubt that world leaders must break out of this “same strategy but different day” cycle of rearranging recommendations and commitments. At the forthcoming G7 Leaders’ Summit in Schloss Elmau, G7 leaders can either continue with the same approach to pandemics or kickstart a new one that makes falling into neglect simply impossible. What does this mean in practical terms? 

Put pandemic prevention, preparedness, and response in the diary. First and foremost, checking up on progress made on pandemic preparedness and response must be a regular fixture in global leaders’ calendars. Just as transnational threats like climate have led to the creation of the annual COP process to catalyze reduction of carbon emissions, pandemics need methodical political attention — and crucially, action — at the highest level. We need “ever-warm” response and accountability in the same way the COVID-19 pandemic proved the need for ever-warm manufacturing capabilities. 

Make pandemic prevention and preparedness a top political priority. Beyond regular meetings, an adequate response to pandemics needs a political engine with processes that assess risks and review progress systematically. The Independent Panel’s May 2022 report calls for “an inclusive leader-level health threats council that can galvanize political commitment to end the COVID-19 threat” — and we agree. The G7 should put its collective heft behind a critically-needed, broader, and inclusive, Global Health Threats Council of leaders to both convene in a crisis and create the momentum to catalyze the implementation of pandemic prevention and preparedness plans, based on new learnings from the COVID-19 pandemic.

Act with urgency at this year’s UN General Assembly. In line with setting such a political engine, we also need to turn it on as soon as possible. We need the world to be in a dynamic state of readiness, not caught unprepared as it was in 2020. A UN Summit on pandemic preparedness and response in the coming months in New York at the leadership level should be at the top of António Guterres’ to-do list. Such a leadership summit would set a standard and help breathe life into plans to regularly convene on pandemic preparedness and response at the leadership level. 

The very fact that many of the recommendations that came out of the Ebola outbreak are now being actioned or overtaken, shows just how little was done to properly implement the learnings from Ebola in 2015. While we are seeing progress on pandemic preparedness, that progress remains fragile amidst competing crises and inconsistent levels of ambition and commitment from all countries and their leaders. The establishment of the Pandemic Prevention, Preparedness, and Response Fund at the World Bank — bolstered by the financial commitments of the U.S., EU, Germany, Indonesia, and Wellcome  — will be instrumental but needs more countries to chip in and demand their seat at the table so that everyone contributes, everyone benefits, and everyone decides. Getting broad buy-in to a Fund that pulls away from the typical donor-led cliché will help set this G7 on the path to success, not obscurity. G7 leaders should affirm their commitment to an inclusive approach to the Fund’s governance, and G7 countries that have not yet pledged should use the opportunity of the Summit to do so.

In brief, Germany’s Chancellor and their G7 counterparts need to make sure pandemics are not only high on the agenda on June 26-28, but more importantly, that there is a new political engine — that goes beyond the G7 — to enable the world to banish the cycle of neglect to history. Acknowledging the elusive and unpredictable nature of pandemics, this would set us on track to effectively deal with present uncertainties, future unknowns, and provide the political forum for cooperation that was so desperately needed when nationalism and parochial interests saw countries pull up their drawbridge right at the moment they should have been opening up to coordination and collaboration early in the COVID-19 pandemic. This is a shift worth making, and one that would stand the test of time at the next German G7 Presidency in 2029.

Call for African Leaders to Support the Pandemic Fund

The COVID-19 crisis has demonstrated the devastating impact that epidemics and pandemics can have on the health, security, and prosperity of Africans. It has accentuated the need for a New Public Health Order for Africa — championed by the Africa Centres for Disease Control and Prevention (Africa CDC) — not in the least because of the gross global inequities in access to medical tools including vaccines, diagnostics, therapeutics, personal protective equipment, and other lifesaving medical countermeasures and supplies that have played out during this pandemic. The COVID-19 pandemic has also underscored the need for Africa to build more resilient health systems and collaborate across borders to be able to prevent, detect, and respond to emerging health threats while addressing ongoing health priorities. 

African civil society organizations (CSOs) have come together to urge leaders of African governments to pledge their support for the proposed new Pandemic Preparedness Fund at the World Bank and to ensure that the Fund advances the aims of the New Public Health Order for Africa through equitable and multilateral support. If well-resourced, the Fund has the potential to be a transformative new source of financing to advance Africa’s health security and to prevent the next pandemic. 

Read the full letter. If your organization is interested in signing on, please reach out to Hanna

 

Pandemic Action Network Statement on the Second Global COVID-19 Summit

The Second Global COVID-19 Summit showed a renewed commitment to end the COVID-19 crisis and prevent the next pandemic threat. Against complacency and pandemic fatigue, leaders from over 35 countries, the private sector, philanthropy, and civil society brought forward new actions and commitments — both financial and non-financial — to meet urgent needs across the summit’s priorities of vaccinating the world, protecting the most vulnerable, and preventing future pandemics. Financial commitments totaled almost US$3.2 billion, with approximately US$2.5 billion in funding from governments, and approximately US$700 million from the private sector, foundations, and other non-government actors.

Statement from Carolyn Reynolds, Co-Founder, Pandemic Action Network

Today’s Global COVID-19 Summit was a win against complacency and has provided a much-needed shot in the arm for both the global COVID response and to begin to prepare the world for the next pandemic threat. We are pleased that the Summit has yielded important new commitments to vaccinate the world, save lives, and nearly US$1 billion to establish a new Fund for global health security and pandemic preparedness. This is a significant down payment and enables the World Bank to move forward on establishing the Fund this summer. But we must maintain the momentum beyond today and political leaders must stay in the fight. This pandemic is not over, and the world must move faster to deliver lifesaving tools and prepare for whatever variant or pandemic threat is coming next. The U.S. Congress must urgently approve additional funding for the global COVID response, and other governments and private and philanthropic partners must step up support for the response and for the Fund as soon as possible.

Statement from Eloise Todd, Co-Founder, Pandemic Action Network

World leaders‘ commitments at the Global COVID-19 Summit today have helped give a much-needed reset to the global COVID response. But without sustained and decisive action, the world could slip into permanent inequity between those that are able to be treated and vaccinated for COVID-19 and those that are not. All eyes are on global and regional bodies to see how they can build on today’s starting shot and deliver real progress by the G7 Summit at the end of June.

As long championed by Pandemic Action Network, equity featured prominently in both reflections on the COVID-19 pandemic and in new commitments. We welcome commitments and new investments to close the funding gap for the Access to COVID-19 Tools Accelerator (ACT-A), solve for last-mile vaccination delivery challenges, accelerate access to generic therapeutics, and diversify manufacturing and procurement of medical countermeasures to build strong and sustainable systems in every region of the world.

Pandemic Action Network was also pleased to see political and financial support for a new Fund for Global Health Security and Pandemic Preparedness from across sectors. As we double down to end the COVID-19 pandemic, we also must look ahead and prepare both for future COVID-19 variants and emerging disease threats. Government leaders from around the world stepped up today to support a new pandemic preparedness fund and advocated for the need to include diverse voices in the design and governance of a new fund. Financial commitments from the U.S., European Commission, Germany, and the Wellcome Trust total nearly US$1 billion, and represent a significant down payment toward the US$10 billion needed annually for this Fund.

But while today’s Summit serves as a needed jolt to the global COVID-19 effort, there is still much work to do. Today’s financial commitments for response sum just over US$2 billion, and while this funding is urgently needed, it’s long overdue and far short of the current ACT-A funding gap (nearly $US15 billion). It is critical that all governments and sectors step up and prioritize significant new resources to end the global COVID crisis — including the U.S. Congress and Administration working together to transcend politics and quickly pass at least US$5 billion for the global COVID-19 response. In addition, it is critical to heed the call from many African leaders for Gavi, the Global Fund, and other vaccine purchasers to prioritize purchases from African vaccine manufacturers to ensure new facilities are sustainable. It will also be important for a diversity of donors and stakeholders to commit to the new Fund for Global Health Security and Pandemic Preparedness to ensure it is inclusive, representative, and effective. 

As we look ahead to the World Health Assembly, G7 and G20 Summits, and UN General Assembly, Pandemic Action Network will stay vigilant to make sure Summit commitments are realized and accountable, and that world leaders are collectively challenging themselves to do whatever it takes to end this crisis for everyone, everywhere.

An African Agenda for Pandemic Preparedness and Response — Policy Brief

As the COVID-19 pandemic persists into its third year, African countries are grappling with the fallout from this multi-year crisis. Widespread loss of life, enduring disability, and broader economic and social fallout of the COVID-19 crisis has made pandemic preparedness an urgent imperative. With momentum around the call for a New Public Health Order for Africa, there is a window of opportunity for substantial policy reform at national, regional, and global levels. This is a window that must not be wasted.

Developed by Future Africa ForumAn African Agenda for Pandemic Preparedness and Response — presents practical and actionable recommendations aimed at enhancing pandemic preparedness and response capabilities and capacities for African policymakers at both regional and national levels. The policy brief is anchored by the State of Play report, a systematic review of African regional policy documents and initiatives relating to pandemic preparedness and response and engagement of civil society stakeholders.

Read the full policy brief here

Call to Action! Accelerating an Effective and Equitable COVID-19 Response and Pandemic-proofing the Future

We are at a pivotal moment in the COVID-19 pandemic. With only 14% of people in low-income countries vaccinated with at least one dose, progress against the disease is at risk. Equitable access to vaccines, tests, and treatments remains elusive, compromising the health of millions of people, increasing the chances of more deadly variants, and endangering recovery. Now Russia’s invasion of Ukraine has brought a new security challenge, further threatening global health and safety. The humanitarian crisis in Ukraine and looming food and energy emergencies will continue to strain economies, people, and systems — not only in Europe, but also in other regions where progress against COVID-19 is still fragile.  

The convergence of different security crises with a still-present COVID-19 emergency will only deepen global suffering unless world leaders act urgently. It is essential that G7, G20, and all leaders not retreat from COVID-19 and acknowledge that ending this pandemic remains critical to the world’s security and stability. It is the time to double down and finish this solvable crisis — before the world is faced with a more transmissible or deadly variant, or even a novel pathogen. 

Together with nearly 30 partners, Pandemic Action Network calls on leaders to revamp their response to the pandemic in upcoming Summits and global coordination meetings taking place in 2022 and stay the course and secure the future, by prioritizing the following actions:

  1. Accelerate equitable access to and acceptance of vaccines, diagnostics, and therapeutics
  2. Provide new, diversified funding to fill country-identified gaps in response and preparedness
  3. Build now to pandemic proof the future

Read the full call to action here

This call to action is open for sign-ons. Please email Hanna if you’d like to add your organization. 

Steps Taken, a Leap Required — CEPI’s Replenishment Statement

Today, as the world reaches a grim milestone of six million official deaths from the COVID-19 pandemic and as Russia wages war in Ukraine, world leaders gathered at the Global Pandemic Preparedness Summit to address what we must do better to prevent and prepare for pandemic threats. The Summit, organized by the Coalition for Epidemic Preparedness Innovations (CEPI) and the U.K. Government, represented a critical opportunity for global leaders to prioritize pandemic preparedness and support CEPI’s groundbreaking 5-year plan to develop life-saving vaccines to help prevent a crisis of similar scale to the COVID-19 pandemic, including its 100 Days Mission to develop safe and effective vaccines in 100 days following an outbreak. 

Pledges of financial and political support were made in nearly equal measure with a total of 13 countries and 2 philanthropic donors pledging US$1.54 billion to CEPI’s US$3.5 billion five-year plan. Japan’s announcement of US$300 million made it the largest contributor, followed by the U.K. in addition to commitments from Australia, Austria, Finland, Germany, Indonesia, Italy, Japan, Mexico, New Zealand, Norway, Singapore, and the U.S. 

At least nine other countries (Brazil, Canada, Greece, Kuwait, Lithuania, Nigeria, South Korea, Spain, and Switzerland) and the European Commission expressed their support, though no specific financial contribution was mentioned. 

While this is a welcome and important first step toward a world that is better prepared for pandemic threats, it is disappointing that many governments failed to match political support with bold and meaningful financial commitments. The COVID-19 pandemic showed us that the world is ill-prepared to prevent and respond to a pandemic caused by a novel respiratory pathogen. The pandemic research and development (R&D) system as it exists does not work to address the challenges of emerging infectious diseases. As we look toward year three of COVID, we are already witnessing the familiar and costly cycle of panic and neglect around pandemics spinning into motion. CEPI’s plan to reduce vaccine development time to 100 days is one in a set of critical measures to get ahead of the cycle of panic and neglect and avoid another trillion-dollar pandemic that needlessly costs millions of lives and livelihoods. 

Eloise Todd, Pandemic Action Network’s co-founder, said:

“While today’s commitments of over US$1.5 billion to CEPI are a welcome and strong start, they are not enough. The COVID crisis showed us that the vaccine R&D system as it exists cannot meet the challenges of emerging infectious diseases before they cause severe damage, nor can it ensure all people everywhere have equitable access to the tools and technologies they need to curb a global health emergency. Leaders can avoid repeating past mistakes and build a system that is forward looking and equitable. Fully funding CEPI is an impactful way to do just that. An investment in CEPI is a fraction of the trillions lost to pandemic response and an investment that pays a multitude of dividends. We expect key global leaders to step up in the coming weeks to align their financial commitments with their political commitments, and make a fully-funded CEPI a reality.”

Pandemic Action Network and its network of over 250 partners will follow up closely on the actions of governments, philanthropies, and decision makers who have expressed their commitment to this goal, especially those key global leaders who can convene other governments, rally support, and mobilize resources. Building on the strong momentum from the Global Pandemic Preparedness Summit, concerted action from world leaders in the coming months will be crucial to fully fund CEPI and ensuring the COVID crisis leaves a legacy of pandemic preparedness.

CEPI’s Unique Impact Opportunity: Pandemic Preparedness & Response R&D

The Coalition for Epidemic Preparedness Innovations (CEPI) was founded with the mission to accelerate the development of vaccines against emerging infectious diseases (EID) and enable equitable access for all during outbreaks. Less than three years after its start, CEPI’s quick response during the COVID-19 pandemic propelled the development and manufacturing of new vaccines and it was the only entity with the mandate to invest in de-risking COVID-19 vaccine research and development (R&D) with global access in mind. CEPI’s role fills some of the critical gaps that governments do not address and on March 7-8, the U.K. Government will host the CEPI replenishment at the Pandemic Preparedness Summit. The replenishment aims to raise US$3.5 billion for the delivery of CEPI’s critical 2022-2026 strategy to accelerate the development of vaccines and other health tools against epidemic and pandemic threats.

Produced by Pandemic Action Network and DSW, CEPI’s Unique Impact Opportunity: Pandemic Preparedness & Response R&D examines the characteristics and ways in which CEPI is distinctly positioned to bolster global and regional health security initiatives, especially through vaccine R&D against EIDs, to ensure the world is equipped to end the COVID crisis for everyone and is better prepared for the next pandemic.

Key messages of the brief explainer include:

  • CEPI is uniquely positioned to address global pandemic threats through vaccine R&D for emerging infectious diseases.
  • Because of its commitment to equitable access for the global good, particularly in low- and middle-income countries, CEPI’s work leads to increased access and distribution of much-needed vaccines to traditionally underserved populations.
  • Building on its role, investments, and relationships, CEPI delivers catalytic impact globally in pandemic preparedness and response.
  • CEPI fills critical gaps in the vaccine R&D ecosystem that would otherwise go unfilled.
  • Emerging infectious diseases, such as COVID-19, do not recognize international borders. CEPI’s global mandate naturally complements regional and national R&D institutions that work to counter pandemic threats.

Read the full brief.

Amplify these messages using our social media toolkit.

 

Calling for Bold Pandemic Action at the EU-AU Summit

African and European civil society organizations (CSOs) call on leaders in advance of the African Union (AU) – European Union (EU) Summit on February 17-18, 2022, to show solidarity in ending not only the COVID-19 crisis but also responding to global epidemics including HIV, tuberculosis, and malaria and put in place mechanisms and resources to build resilience and prepare for future pandemics. It’s time for strong and sustained political will, collective alignment, and integrated end-to-end approaches. We call on leaders to adopt the following actions at the Summit:

  1. Tackle the crisis of inequitable access to COVID-19 vaccines, and support vaccination programs
  2. Address the crisis of inequitable access to COVID-19 tools, including tests, treatments, oxygen, and PPE
  3. Invest in and strengthen the research and development (R&D) capacity in Africa
  4. Support Africa’s mRNA Technology Transfer Hub and agree to waive intellectual property (IP) for COVID-19 vaccines and other medical tools
  5. Support health systems strengthening in African countries to enable prevention, detection and response to new and existing threats
  6. Reform and strengthen multilateralism

Humanity deserves a world where every country is equipped to end the COVID-19 crisis and every country is prepared to stop infectious disease outbreaks from becoming deadly and costly pandemics. 

Read the full letter

Pandemic R&D Agenda for Action: Fostering Innovation to End This Pandemic and Prepare for the Next One

As the world commences the third year of the COVID-19 pandemic, the case for investment in research and development (R&D) for medical countermeasures to prevent and combat emerging global health threats is stronger than ever. Despite tremendous scientific accomplishments in 2020-21, systemic gaps in pandemic-related R&D systems, supply chains, manufacturing, and delivery continue to stymie the roll-out of urgently needed technologies to all people who need them, everywhere, and are prolonging the pandemic.

COVID-19 and its variants have exposed longstanding market and systems failures and fragilities that pose barriers to timely and effective pandemic R&D. Not only do these persistent gaps threaten to undo progress achieved through the scientific breakthroughs, but they also exacerbate entrenched inequalities that leave the most vulnerable and disadvantaged people around the globe without access to lifesaving medical countermeasures and essential health services, and perpetuate gross power imbalances between high- and low-income nations. COVID-19 has also unleashed a multitude of actors in pandemic-related R&D across the innovation spectrum and across the globe, underscoring the growing need for more purposeful alignment, coordination, information-sharing, and transparency.

The world urgently needs a fit-for-purpose, proactive, and resilient pandemic R&D ecosystem. There is broad consensus that R&D is a vital component of building a world better equipped to prevent, prepare for, and respond to pandemic threats. Yet new investments in innovation will fail to meet their promise to save lives, prevent future global health emergencies, and build a healthier, safer world for all unless governments, international institutions, and industry are willing to heed the hard lessons of this pandemic and work together to fix these systemic failures and challenges.

Produced by Global Health Technologies Coalition and Pandemic Action Network with contributions by members of the Pandemic Action Network’s Pandemic Preparedness Working Group, this policy brief calls on world leaders to prioritize action in four key areas to close the critical R&D, manufacturing, and delivery gaps necessary to end the acute COVID-19 crisis and build a more resilient, equitable pandemic R&D ecosystem for the future.

Read the full brief here.

Personal Protective Equipment for Frontline Health Workers: An Essential Component of Pandemic Preparedness & Response

In December 2020, Pandemic Action Network’s Pandemic Action Agenda series urged world leaders to strengthen global health security architecture and governance in key areas, including pandemic supplies, to increase accountability and ensure the world is better prepared for the next pandemic and to respond to COVID-19.

This brief takes stock of progress made since December 2020 to resolve the global personal protective equipment (PPE) access crisis, aims to assess supply and demand challenges specific to community health workers, and informs recommendations for world, regional, and national leaders to build a more reliable and sustainable emergency response supply chain for the future.

Today, we have compelling evidence of the risk of leaving frontline health workers unprotected or partially protected against COVID-19, and we still lack sustainable solutions. As we look toward year three of this pandemic and beyond, world, regional, and national leaders must learn the lessons of this crisis and continue to prioritize sufficient PPE for frontline health workers — especially those who serve the most vulnerable and hardest-to-reach populations.

Read the full brief here.

Exclusion of Pandemic Financing in the Build Back Better Act Statement from the Global Health Council’s Global Health Security Roundtable Co-Chairs

“We are disheartened that, in the middle of the ongoing COVID-19 pandemic, one of the compromises made in the agreement on the Build Back Better Act was to cut out financing for future pandemic preparedness. While we welcome the needed US$1.3 billion to support expanded global vaccine production capacity and research on infectious diseases, the bill leaves out critical elements of President Biden’s American Pandemic Preparedness Plan, including the US$600 million requested to stand up a new multilateral fund to bolster global preparedness for future pandemics.

We represent dozens of organizations who have been calling for U.S. global leadership to establish such a fund to address pandemic threats. Establishing this fund is a long overdue step  toward addressing the years of chronic underinvestment that left America and the world vulnerable to COVID-19. There is strong bipartisan support for the fund from both the House and the Senate and from leading global finance and health experts, who have urged that the fund be set up swiftly and capitalized at US$10 billion per year over the next five years. While the US$600 million U.S. contribution to the fund that was included in the Biden Administration’s Pandemic Preparedness Plan represents only a fraction of the global need, it is an urgent first step toward helping prevent another devastating pandemic from happening again.

Omitting this critical funding from the bill will signal a return to complacency in the face of one of the most looming threats to our national and global security. And it will signal to other countries that President Biden’s signature initiative to establish a new fund to fight pandemics  — which he touted to world leaders at the Global COVID-19 Summit just one month ago as a key piece of his plan to Build Back Better — is not backed by any serious financial commitment or urgency from the United States. The White House and Congress should urgently agree to ensure the US$600 million for the multilateral fund is included in the Act before final passage and then urge other countries to join the U.S. and contribute their fair share.”

Partnering to Advance Health Security in the Middle East and Around the World

The global response to COVID-19 has shown that the world was ill-prepared to prevent and rapidly respond to a novel pandemic threat. Despite repeated warnings of the increasing threat of epidemics and pandemics, both public and private sector actors have failed to prioritize the forward-looking investments, systems, and structures that are necessary to ensure that life saving tools and medical countermeasures are ready to deploy to curb the spread of disease before it becomes a global health emergency.

When COVID-19 emerged in early 2020, the Kingdom of Saudi Arabia (KSA) determined that urgent and unprecedented action would be required. In response, the government mobilized emergency surge funding to kickstart research and development (R&D) of new medical countermeasures. As President of the G20 at the time, KSA in April 2020 partnered with the Coalition for Epidemic Preparedness Innovations (CEPI), investing US$150 million to help fuel the development of COVID-19 vaccines for global use. With this timely support, CEPI was able to leverage additional funding, expertise, and know-how from around the world to accelerate COVID-19 vaccine development with the aim of enabling rapid global, equitable, and affordable access to vaccines to save lives and slow the spread of the virus.

Although COVID-19 vaccines were developed in record time, most low- and middle-income countries have been left far behind their high-income country counterparts in terms of vaccine access. Without widespread global vaccination, the COVID-19 virus will continue to spread unchecked in many parts of the world, risking the emergence of new variants that can withstand existing vaccines and therapeutics while threatening to undo the progress that has been made. This underscores the urgent need to immediately ramp up the supply and delivery of COVID-19 vaccines to get more jabs in arms and reach the 70% global vaccination goal set at the Global COVID-19 Summit.

Produced by the Future Investment Initiative Institute and Pandemic Action Network, The Kingdom of Saudi Arabia: Partnering to Advance Health Security in the Middle East and Around the World calls for strategic investments in CEPI to be made by KSA and global partners to answer the call for increased, more predictable, longer-term, and sustainable funding for vaccine R&D, thus addressing variants and preparing the world for future pandemics.

Read the full report here.

Bridging the Innovation Gap to Prevent the Next Pandemic — Policy Brief

The world was woefully unprepared to prevent or rapidly respond to the COVID-19 pandemic. This is the result of decades of failure by national and global policymakers to address pandemics as a systemic and growing threat. A glaring weakness is that the ecosystem for pandemic preparedness research and development (R&D) — the system that is meant to develop vaccines, treatments, and other tools for known and unknown health threats — is rife with market and systems failures that prevent it from operating efficiently, effectively, and equitably.

While pandemics can affect the whole world and create large, global markets for vaccines, treatments, and other technologies, those markets have repeatedly failed to respond with the foresight and urgency needed to match the scale, scope, and unpredictability of pandemic threats. The world must urgently address the persistent market and systems failures in the global health R&D ecosystem to prepare for the next pandemic threat.

This policy brief, prepared by Pandemic Action Network, covers the market and systems failures in the pandemic preparedness R&D ecosystem and lays out the unique role that the Coalition for Epidemic Preparedness Innovations (CEPI) plays in leveraging partnerships and incentives to counter the failures as one key step in building a smarter, more effective and equitable pandemic R&D ecosystem.

Read the policy brief here and the full analysis here.

Pandemic Action Agenda: What World Leaders Should Do to Help Prevent the Next Pandemic

With global COVID-19 cases set to surpass 50 million and spiking across the United States and Europe, world leaders are gathering in a series of international summits to discuss what they will do to stop the pandemic. The current crisis demands urgent and united action as a global community, as no country will be safe from the virus until every country is safe.

But this pandemic didn’t have to happen, and the next one won’t wait. As they fight the current battle, leaders must also take steps NOW to bolster our global and national defenses against emerging pandemic threats before they materialize.

Synthesizing lessons of what has gone wrong in COVID-19 and in previous outbreaks and epidemics, the Pandemic Action Network’s Global Health Security Architecture Working Group has identified six priorities for international action to ensure the world is better prepared for the next pandemic. These are captured in our brief Pandemic Action Agenda paper released last month.

Pandemic Action Agenda Series

Now we’re pleased to release a series of Pandemic Action Agenda papers which expand on each of the six priority areas for action:

Pandemic Action Agenda Summary: Calling on world leaders to strengthen the global health security architecture and governance and make the world better prepared for pandemics.

Global Health R&D: Bolstering the global research and development architecture for health security.

Outbreak Detection: Enhancing the availability and use of reliable data and early warning systems to drive more effective preparedness and response to outbreaks.

Pandemic Financing: Mobilizing sufficient funding for national pandemic preparedness and global response efforts.

Country Capacity: Enhancing countries’ capacity to prevent and respond to outbreaks through technical assistance and improving health security infrastructure.

Pandemic Supplies: Solving supply chain bottlenecks and ramping up regional and local production and delivery to ensure health workers everywhere have access to sufficient quality personal protective equipment (PPE) and other frontline health supplies.

Metrics and Evaluation: Increasing accountability through more effective mechanisms to assess—and fill gaps in—country preparedness levels. COMING SOON

What You Can Do

Advocate for action. Help us deliver the Pandemic Action Agenda directly to key decision-makers in your country and international organizations, and press them to take action on these issues. Contact Naomi Komuro at [email protected] and let us know who you can reach (or we can give you ideas!).

Spread the word. Share the #PandemicActionAgenda on your social media channels and through other communications within your networks to help build us momentum to prioritize global preparedness. Find the social toolkit here.

Hold leaders to account. Sustained advocacy and communications are essential to avoid repeating the cycle of panic and neglect when it comes to deadly outbreaks. Follow up with decision-makers through emails, meetings or events, and ask them share what they are doing to respond to the Pandemic Action Agenda—and let us know what you learn to inform our ongoing advocacy efforts.

Every effort we make in the fight against COVID-19 should leave a longer-term legacy that better prepares humanity to more effectively deal with outbreaks and pandemics and—when possible—to prevent them at the source.

Want to learn more? Please contact Carolyn Reynolds, Co-Founder, Pandemic Action Network at [email protected]

Do Whatever It Takes! Making the COVID-19 Summit a Step Change in Global Response

Pandemic Action Network is relentlessly focused on ending the COVID-19 crisis everywhere and preventing the next pandemic. We work with our global network of more than 140 partners to push governments to bridge the divide between rhetoric or piecemeal efforts and meaningful actions. When we first learned about the prospect of a global COVID-19 Response Summit — something we have been calling for over the past 18 months — we set out to define the step change in ambition that leaders would need to take after the devastatingly inadequate action taken to tackle this pandemic crisis to date.

That’s why in advance of this Summit, we worked with our partners at the COVID Collaborative and across multiple centers at Duke University to bring more than 60 organizations together around a common position on what’s needed to end this crisis. We’re pleased to see much of what we have been calling for reflected in the Summit targets, which we support. But this Summit has to set itself apart by being the starting point in a much longer journey.

It’s beyond time for an action plan, leadership, and accountability. The world is divided between the haves and the have nots like never before. Those with access to COVID-19 vaccines, and those with no access in sight. We have to change this, and at the 22 September COVID-19 Summit, leaders must pledge to do whatever it takes to fully vaccinate 70% of the population in every country in less than 12 months. We will be tracking their progress towards that commitment and the interim target of at least 40% by the end of 2021.

To get there, we must dramatically ramp up support NOW for:

  • Vaccine donations, queue swaps, manufacturing, and delivery
  • Development and deployment of testing and treatments — including oxygen — and PPE
  • A strong frontline health workforce to reach the most vulnerable communities

We make our own commitment to deliver. We will continue to help mobilize the political support and resources necessary to deliver the targets, and track progress of countries towards their goals. We will also push the private sector and philanthropic donors to play their part in delivering the funding — and the policies — to achieve global vaccination and delivery of COVID-19 tools. We will convene and tap the deep expertise and capabilities in our Network across sectors to inform their design and ensure they are inclusive, accountable, sustainably funded, and commensurate with the threat.

It’s time to shine a light on the problems in the system, and fix them, before they take more lives. We are in a race against time. The world has the resources and the ingenuity to solve these challenges.

It’s a matter of leadership and political will. We will be working to ensure that this Summit leaves a legacy to end this crisis and pandemic-proof the world once and for all.

Read and share the full Framework for a Global Action Plan for COVID-19 Response endorsed by more than 60 partners here.

Addressing Market Failures: The Role of CEPI in Bridging the Innovation Gap to Prevent the Next Pandemic

The global response to COVID-19 not only shows that the world was ill-prepared to prevent and respond to a pandemic caused by a novel respiratory pathogen, but also that there are an array of system and market failures in global health research and development (R&D). Solving for these failures ― and building a ready and sustainable R&D ecosystem for pandemic preparedness ― will be critical to advancing global health security and preventing future infectious disease outbreaks from becoming the next deadly and costly pandemic.

Addressing Market Failures: The Role of CEPI in Bridging the Innovation Gap to Prevent the Next Pandemic, produced by Volta Capital, Pandemic Action Network, and the Africa Centres for Disease Control and Prevention (ACDC), examines global health R&D failures to help inform policy and funding decisions to bolster preparedness and response for emerging pandemic threats. In particular, the paper considers the unique role of CEPI in addressing some of these failures, its strengths and challenges in the COVID-19 response, and the role it can play through its new strategy to bolster future epidemic and pandemic preparedness.

Key findings of the paper include:

  • Longstanding and persistent market and systems failures in global health R&D, especially for vaccines against novel pathogens, have left the world at grave risk of deadly and costly pandemics.
  • The world cannot wait for the next pandemic to bolster investments in R&D and preparedness for emerging infectious disease threats.
  • CEPI has a key role to play in a better prepared global R&D ecosystem.

To learn more, read the full analysis Addressing Market Failures: The Role of CEPI in Bridging the Innovation Gap to Prevent the Next Pandemic and the accompanying policy brief.

Share the key messages using our social media toolkit.

Framework for a Global Action Plan for COVID-19 Response

We are at an exceedingly perilous and urgent moment in the COVID-19 pandemic. As the Delta variant has demonstrated, we are fighting a virus that doesn’t respect borders and rapidly advances across continents. If the virus continues to circulate unchecked in large parts of the world, we will see not only many more millions of infections and deaths, but also new variants that could totally pierce vaccine immunity, returning the world to square one. The global COVID-19 crisis demands leadership and a global plan of attack. A coordinated, global response, the only possible successful response to the pandemic, must be grounded in equity at all levels – global, regional, national, subnational and community. An “all hands on deck” crisis response must deploy all available resources and capabilities – multilateral and bilateral, public and private sector. A robust and effective response to the current crisis is also the best foundation for health systems strengthening and future pandemic preparedness. World leaders should therefore urgently convene a “Global Pandemic Response and Vaccination Summit” and commit to urgent actions detailed in our Framework For a Global Action Plan for COVID-19 Response. Read more here.

An “all hands on deck” crisis response must deploy all available resources and capabilities – multilateral and bilateral, public and private sector. A robust and effective response to the current crisis is also the best foundation for health systems.

 

Calling for a New Multilateral Financing Mechanism for Global Health Security and Pandemic Preparedness

People and countries around the world continue to suffer from the devastating human, economic, and social costs of being unprepared for a deadly pandemic like COVID-19. This crisis is a call-to-action. World leaders must seize this opportunity to leave a legacy of a healthier and safer world — starting with a new global financing mechanism that provides robust and sustained investments in pandemic prevention and preparedness. At the 2021 United Nations General Assembly, world leaders should launch a 100-day action plan to establish and resource a new financing mechanism, or Fund, that can mobilize at least US$10 billion annually over the next five years to bolster global health security and pandemic preparedness. History has shown time and again that if action is not taken during a crisis, then political will dissipates once the crisis fades from view. An expedited timeline for establishing the Fund will provide a critical new tool for the ongoing COVID-19 response efforts and create continuity between the pandemic response and recovery activities while bridging to escalated and sustained efforts on pandemic preparedness.  This policy brief, prepared by contributors from the Center for Global Development, Pandemic Action Network, and Nuclear Threat Initiative, is intended to inform and guide ongoing conversations among governments and non-governmental stakeholders on the parameters and design of the new Fund and action plan. Read the policy brief here.

This policy brief, prepared by contributors from the Center for Global Development, Pandemic Action Network, and Nuclear Threat Initiative, is intended to inform and guide ongoing conversations among governments and non-governmental stakeholders on the parameters and design of the new Fund and action plan.

UN General Assembly Called Upon to Lead Global Pandemic Prevention and Preparedness

Civil society leaders urge UN General Assembly President Volkan Bozkir to use the informal plenary on July 28 to formally start the process for a UN High-Level Summit on Global Health Security and Pandemic Prevention and Preparedness during the 76th session of the General Assembly.

Your Excellency,  

On behalf of the Pandemic Action Network and our partners around the world, we welcome the announcement of an informal plenary of the General Assembly on 28 July to discuss what the world needs to do to prevent and prepare for future pandemics, informed by the findings and recommendations of the Independent Panel for Pandemic Preparedness and Response (IPPPR) and other review efforts. The devastating health, economic, and social impacts of this deadly, costly, and protracted global crisis underscore that it is well past time for the community of nations to prioritize and prepare for pandemics as the existential, catastrophic, and growing global security  threats they are. We urge you to ensure that the outcome of this plenary is a commitment to a concrete, time-bound political process for international action on pandemic prevention and preparedness. 

Specifically, we urge you to use the 28 July 2021 informal meeting to kick off a formal process and set a date during the 76th session of the General Assembly — ideally within the first six months or no later than September 2022 — for a UN High-Level Summit on Global Health Security and Pandemic Prevention and Preparedness at the Heads of State or Government level. The Summit should agree to a Political Declaration or similar, which outlines a set of concrete solutions, backed by the requisite financing, institutional, and policy reforms, and member state commitments, that will ensure an international system better prepared to detect, prevent, and respond to pandemic threats. Given the whole of society nature of  pandemics, it will be essential that the Summit fully and actively engage leaders of multilateral institutions, civil society organizations, private sector, foundations, academic, and research institutions alongside government leaders. 

The proposals from the IPPPR, the G20 High-Level Independent Panel on Financing the Global Commons for Pandemic Preparedness and Response (G20), the Global Preparedness Monitoring Board (GPMB), our Network, and others have been based on robust evidence, deep consultation, thorough analysis, and active debate before and during the COVID-19 pandemic. There is a striking convergence of recommendations around the global financing, governance, and accountability reforms that are urgently needed; what has been sorely lacking is political will to act.  

While accelerating the global COVID-19 response remains the most urgent priority, we cannot afford to wait until this pandemic is over to begin to bolster our collective defenses against emerging pandemic threats. Now is the time to lay the foundation for a resilient international system that can act quickly and equitably to prevent a health emergency of this scale from occurring in the future. Too often, political will for system change recedes as a crisis wanes. World leaders must seize this opportunity to commit to pandemic-proof the future and leave a legacy of a healthier and safer world. 

Pandemic Action Network and our partners stand ready to work with you to support this process. Thank you for your urgent attention to this matter, and we look forward to your reply.  

Sincerely, 

Carolyn Reynolds 
Co-founder
Pandemic Action Network  

On behalf of:

 

If your organization would like to sign on, please email Hanna Hwang

Call-to-Action: Global Roadmap to Vaccinate the World

There is currently no plan to get to global herd immunity, needlessly leaving the world vulnerable to case resurgence and the proliferation of variants. We are calling on leaders to agree to a Global Vaccine Roadmap to achieve global herd immunity as soon as possible (at least 70%, more if the evolving science points to the need for further coverage). This Roadmap should:

  1. Set out a comprehensive, coordinated strategy to get to global herd immunity as soon as possible.
  2. Increase and improve the global supply of all COVID tools through investment, policies, and the redistribution of excess doses.
  3. Fully cost the response, agree to a burden-sharing model, and begin to plug the gap by fully funding the Access to COVID-19 Tools Accelerator (ACT-A).

Most existing funds are mainly focused on procurement, yet multiple analyses show that it will take hundreds of billions of dollars on top of procurement financing to fully deliver a global response. If successful, ACT-A, for example, will provide vaccines for 27% of low- and middle-income (LMIC) populations in 2021 on current financing levels — but ACT-A finance does not cover rollout costs from “tarmac to arm” of its own vaccines. The situation in India also underscores the importance of oxygen and other tools that are needed before herd immunity is reached. We need a fully-funded, holistic response. We are therefore calling on leaders to:

Set out a comprehensive, coordinated strategy, as has been called for by the IMF, World Bank, WHO, and WTO, to get to global herd immunity as soon as possible, which:

  • Gives countries the support they need so that all efforts to deliver the global response are mapped, efforts are mutually-reinforced, duplication can be avoided and critical gaps can be identified and filled.
  • Delivers a comprehensive costing and analysis covering all elements of a global response to establish what is already covered and identify gaps in supply, procurement, and resources needed in-country for the delivery of vaccines, tests, and treatments.

Increase and improve the global supply of all COVID-19 tools through investment, policies and the redistribution of excess doses.

  • Scale up the production of tests, treatments, and health commodities, including oxygen, and accelerate LMIC-led research and development (R&D) through fully-funded diagnostics and therapeutics pillars.
  • Increase vaccine manufacturing through investments in regional capacity and back policies to increase knowledge sharing, remove trade-related barriers, and create tech transfer hubs.
  • Ensure vaccines are offered at an affordable price and on a not-for-profit basis.
  • Prioritize dose-sharing. G7 leaders should pledge 2 billion doses at the Leaders’ Summit, delivering 1 billion by the end of August and the second billion by the end of 2021 and as part of this delivery, ensure that 250 million additional people in low-income countries (LICs) and LMICs have actually received their doses by the end of August in parallel with national vaccine rollout plans.

Fully cost the response, agree to a burden sharing model, and begin to plug the gap by fully funding the ACT-A.

  • Agree to a burden-sharing model to set out fair share contributions and fully funding ACT-A.
  • Leverage funding opportunities by identifying new funding streams to protect official development assistance (ODA).
  • Fully fund global vaccination to reach 70% coverage, requiring at least US$50B according to IMF estimates, with more in grants needed to enable LMICs to cover the full costs of delivery.
  • Work with countries to urgently cost all delivery needs outside of ACT-A’s mandate so vaccines and other tools can be distributed and administered, including the costs of frontline and community health workers.

Three key deliverables for the G7: leadership, supply, and finance 

G7 leaders must:

1. Develop a Global Roadmap to Vaccinate the World: 

  • Develop a comprehensive, coordinated strategy that plugs gaps and shines a light on the blind spots of current efforts, including delivery of tools to low-resource settings.
  • This Global Roadmap should be kicked off at the G7 Summit and delivered with full costings and logistical, human, and financial resource needs by the end of June at the latest, when other costings will also be available to inform the roadmap.
  • There are growing calls for leaders to step up and set out the plan that is designed to bring the acute phase of the pandemic to an end and vaccinate the world. As well as the proposal from the IMF, World Bank, WHO, and WTO, the Spanish Government has set out a ‘Vaccines for All’ plan, more voices in the U.S. are calling on the Biden Administration to show leadership, and in the vacuum left by the lack of a truly global response, other organizations are stepping up to offer policy prescriptions for a global plan. The report of the Independent Panel on Pandemic Preparedness and Response also recognized the lack of global coordination and political leadership during this pandemic and called for a Global Health Threats Council to be formed.
  • The G7 must not delay in corralling leaders to deliver a Global Roadmap. The UK Presidency is well placed to work hand in glove with the G20 to deliver a comprehensive roadmap that plans to vaccinate at least 70% of people in the world and provides the support needed for every country to get the vaccine delivered and administered safely to 70% of each country’s population.


2. Increase the supply of vaccines available globally by: 

  • Prioritizing dose-sharing. The G7 should pledge 2 billion doses at the Leaders’ Summit, delivering 1 billion by the end of August and the second billion by the end of 2021 and as part of this delivery, ensure at least 250 million additional people in LICs and LMICs have actually received their doses by the end of August. Without dose-sharing, G7 countries would have enough supply to vaccinate to share over 3 billion excess doses even after vaccinating 70% of their own populations.
  • Scaling global capacity to produce COVID-19 vaccines by the end of 2021 through investments in regional capacity, backing policies to increase knowledge sharing, removing trade-related barriers, and creating tech transfer hubs.
  • Buying vaccine supply for COVAX and other mechanisms to help reach 70% coverage.


3. Fully finance the global response to COVID-19 by: 

  • Fully funding global vaccination to reach 70% coverage, requiring at least US$50B according to IMF estimates, with more in grants needed to enable LMICs to cover the full costs of delivery, on the basis of a clear burden-sharing agreement, which will:
    1. Fill the immediate ACT-A funding gap of US$19B.
    2. Commit in principle to fund the global roadmap to get to 70% global coverage on the basis of a clear burden-sharing agreement, finding new resources and protecting existing ODA.
    3. Leverage multilateral development banks (MDBs) to help finance the global roadmap.
  • Ensuring the costs needed to administer vaccines — including to health systems and health workers, including frontline and community health workers — are also met, so that vaccines are not just available but also administered, as part of a fully-costed global plan to reach global herd immunity.
  • Costing and then mobilizing the additional finance needed to deliver this plan to vaccinate the world, using all possible finance tools to raise the amounts necessary, including, but not limited to, SDRs, funds from MDBs, and new sources of funding, including innovative mechanisms and providing finance beyond government funding.

 

                           PATH                 

 

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It’s Time to Pandemic-Proof the World: A 2021 Agenda for Action

The devastating health, economic, and social impacts of the COVID-19 global health crisis show that it is well past time for world leaders to prepare for pandemics as the existential, catastrophic, and growing global security threat they are. In 2010, well before COVID-19, there were six times more zoonotic spillover events than in 1980, and the number of new outbreaks continues to grow. Persistent gaps in international pandemic preparedness and response capacities have been flagged by various expert panels in the wake of previous health emergencies, but time and again, once the crisis disappears, political attention and funding shifts to other priorities. This dereliction of duty must stop once and for all.

Despite impacting people around the globe, COVID-19 has not affected everyone equally. The pandemic has exposed and exacerbated long-standing health and socio-economic inequalities within and across countries and in marginalized and vulnerable populations, including inequalities due to gender, race, ethnicity, class, and disability. The glaring disparities in global access to lifesaving COVID-19 vaccines, therapeutics, diagnostics, and vital tools such as oxygen and personal protective equipment (PPE) underscore the inequitable global health and preparedness system. And the lack of proactive attention by leaders to address and account for these inequities has significantly undermined the global COVID-19 response.

As the Global Preparedness Monitoring Board (GPMB) made clear in its September 2020 report A World in Disorder, the world cannot afford to continue to ignore or delay preparations to bolster our collective defenses against emerging pandemic threats. As they battle the current crisis, countries and international institutions must act now to ensure the world is better prepared for the next pandemic threat, which may be lurking just around the corner. These commitments should include building and reliably funding a well-trained and well-equipped health and research workforce, more resilient frontline health systems, timely and transparent disease surveillance, and effective supply chains for vaccines, diagnostics, PPE, and other tools to enable every country to detect, prevent, and rapidly respond to outbreaks before they become deadly and costly pandemics. It is time to invest in a smarter, more responsive, and more resilient global health security architecture.

Pandemic Action Network’s 100+ partners urge world leaders to take urgent action in the following areas to bolster the global COVID-19 response, hasten an end to this global crisis, and lay the groundwork for a more pandemic-proof world.

Support an equitable global response to COVID-19

The only way to end this pandemic is to end it for everyone through a coordinated global response. Yet as world leaders navigate the second year of responding to COVID-19 and securing vaccine doses for their constituents, nationalist inequitable approaches are still pervasive. Recent data shows that the world has now procured enough COVID-19 vaccine doses to reach herd immunity globally, but while some high-income countries have secured multiple times the number of doses as there are eligible adults in their countries, only 0.2% of doses administered have been in low- and middle-incomes countries (LMICs). Although it may seem intuitive for governments to first take action at home, this approach belies the fact that the virus — and its swiftly spreading variants — do not respect borders. Many countries that managed to control or even stop the spread of the virus earlier in the pandemic are once again seeing a surge in cases. There simply is no effective domestic response without also embracing a global approach. Everyone deserves to hope for a swift end to the pandemic, regardless of where they live. But it will only be possible if political leaders act globally as well as locally, knowing no country will be safe until every country is safe.

1. Accelerate global access and delivery of COVID-19 vaccines needed to achieve at least 70% coverage in all countries and enable an equitable global response and recovery.

World leaders should:

  • Fully fund the Access to COVID-19 Tools Accelerator (ACT-A) in 2021, filling the $22.1 billion funding gap as soon as possible with countries paying their fair share for this global public good. Countries should also commit to continue to invest in research and development (R&D) as well as scale-up of proven tools to prevent, test, and treat COVID-19 and ensure that medical countermeasures are effective against all strain mutations and all variants of concern. Given the scale of resources required, countries will need to tap into fiscal stimulus funding and other financial sources beyond official development assistance (ODA).
  • Agree to a roadmap to achieve at least 70% coverage of vaccines for LMICs, with at least 30% being secured, delivered, and administered in 2021. Leaders need to agree to a fully costed plan to achieve equitable global coverage as soon as possible. The full costs of delivering and administering doses in-country should be included in this roadmap, as well as the investments in vaccine education required to increase vaccine confidence.
  • Commit to donate, free of charge, all excess COVID-19 vaccine doses to the COVAX facility in parallel to their domestic vaccination efforts and start those donations as soon as possible. Countries should immediately announce commitments to share their full surplus supply on the most ambitious timeline possible, putting plans in place to deliver on this commitment as soon as is feasible in 2021 in line with COVAX’s dose sharing principles. These donations should not count as ODA, and should be in addition to funding the ACT-A.
  • Commit to “slot swaps” as another way to give COVAX additional supply. “Slot swaps” should be undertaken whereby high-income countries reallocate some of their existing orders immediately, potentially ordering replacement vaccines to arrive farther in the future, effectively giving their earlier “slots” to COVAX to help provide vaccines for LMICs to close the current acute gap in supply.
  • Ramp up global access and delivery of rapid testing, medical oxygen, and personal protective equipment to the frontlines. Continuing shortages of PPE and medical oxygen for frontline health workers and extremely limited deployment of testing — including genetic sequencing capacity to detect variants of interest — especially in LMICs, is hampering the global COVID-19 response and is a rate limiting factor for global rollout of COVID-19 vaccines and restoration of essential health services.

Prioritize and invest in pandemic preparedness and prevention

According to the IMF, the pandemic will cost the global economy and the World Bank projects that more than 160 million people will fall into poverty by the end of 2021. Conversely, recent estimates are that as little as $10-20 billion annually can ensure the world is much better prepared to detect, prevent, and respond to the next infectious disease outbreak before it becomes another deadly and costly pandemic. To minimize human lives lost from infectious diseases and lessen the impact on countries due to economic fallout, leaders should take the actions below to be prepared for the next pandemic.

2. Establish a catalytic, sustainable multilateral financing mechanism that is dedicated to promoting pandemic preparedness and prevention.

World leaders should:

  • Pledge new investments toward a target $20 billion initial capitalization co-funded from public, private, and philanthropic sources. Priorities for this new multilateral financing mechanism — which will fill a strategic gap in the existing global health architecture — should be on supporting LMICs to develop and implement national action plans for health security and pandemic preparedness, to close their urgent health security gaps, and foster a global “race to the top” among all nations for preparedness. The catalytic nature of this mechanism will help ensure both countries and other global health initiatives prioritize coordinated, multisectoral, prevention and preparedness funding in their domestic budgets, including support for country-level programmatic and managerial capacity in health systems strengthening.
  • Align funding with target country priorities to strengthen pandemic preparedness and containment as well as promote efforts toward pandemic prevention. Programs that should be financed at scale include detecting and stopping the spread of outbreaks and ensuring compliance with the International Health Regulations (IHRs), strengthening laboratory and manufacturing capacity, bolstering and protecting a trained, compensated health workforce, building and strengthening health information systems, ensuring resilient national and regional supply chains, One Health initiatives, and stopping zoonotic spillover from causing new outbreaks through measures such as reductions in deforestation and wildlife trade.

3. Bolster financing and at-the-ready global R&D capacity and coordination to combat emerging infectious diseases and pandemic threats without undermining important funding for existing epidemics research and innovation, including poverty-related and neglected diseases.

Applying the lessons learned from COVID-19, leaders should support the development and financing of mechanisms and initiatives that coordinate and catalyze research and development for new tools, including the Coalition for Epidemic Preparedness Innovations (CEPI), Global Antibiotic Research and Development Partnership, and other not-for-profit product development partnerships (PDPs) addressing the broad range of health threats.

World leaders should:

  • Fully fund CEPI’s $3.5 billion replenishment. This funding would support the organization’s moonshot initiative of compressing vaccine development for new pandemics to 100 days, and continuing efforts to develop vaccines for known threats. It would also support CEPI’s other objectives, including preparing clinical trial networks to quickly respond to new threats, coordinating with global regulators to streamline vaccine oversight, and linking manufacturing facilities to speed up global production.
  • Support integration of R&D into the Global Health Security Agenda (GHSA) framework to include R&D capacity-building for medical countermeasures. Inclusion of metrics through a GHSA R&D taskforce will help countries assess, prioritize, and better plan for strengthening their R&D capabilities.
  • Build on the ACT-A’s response to COVID-19 to ensure a robust, end-to-end, and sustainable investment in global health R&D for pandemic preparedness, including long-term investments to strengthen global research, laboratory, and manufacturing capacities. This future readiness state should also foster more investments and partnerships with diverse research and academic institutions to both build regional R&D prior to crises and scale up support during emergencies. Investments should be made with policies that promote equitable global access to and affordability of tools like vaccines, diagnostics, and therapeutics.

4. Strengthen global and national surveillance capacities & outbreak analytics.

COVID-19 has demonstrated global gaps in early detection and data sharing around emerging threats, as well as gaps in ongoing surveillance capacities of countries, especially low-resource countries. Current emerging infectious disease surveillance and investigation is poorly allocated, with the majority of the globe’s resources not focused on areas with the most zoonotic hotspots where the next emerging deadly pathogen is likely to originate.

World leaders should:

  • Strengthen integrated national disease surveillance capacities in LMICs. Such surveillance capacities should take a One Health approach and be responsive to local needs (i.e., give results in real-time for use by clinicians and public health officials). Such capacities should not be developed in a silo for pandemic risk monitoring; rather they should provide utility for day-to-day public health programs, leverage the latest developments in digital tools to streamline operations for health workers, and accelerate data flow and analysis.
  • Strengthen mechanisms and platforms that allow for independent sharing and verification of data related to emerging health threats, complementary to and in partnership with the WHO’s role in collecting data from official sources under the IHRs. Such capacities should enable and promote more transparency and accountability in data access for all relevant stakeholders.
  • Commit to the rapid publishing and sharing of line list and pathogen genome data into shared repositories (e.g., the Global Influenza Surveillance and Response System and the International Nucleotide Sequence Database Collaboration) to ensure that data necessary to monitor variants of concern can be acted upon before they become dominant.
  • Support innovations in outbreak detection and analytics capacity nationally through emergency operations centers, regionally through academic centers of excellence, and globally through laboratory and disease surveillance networks. The ACT-A has taught the community about the importance of collaboration and rapid response, and these lessons should be applied to future tools.

5. Bolster global capacities, institutions, and systems for pandemics, health security and resilient health systems, including through reforming WHO and strengthening international frameworks for pandemic preparedness and response.

World leaders should:

  • Build consensus for, and rapidly move to implement, proposals that will strengthen the WHO as the global coordinating authority on health. Leaders should support proposals for sustainable financing of the WHO, including incremental increases in assessed contributions and more (and more flexible) voluntary financing. Such resourcing should go hand-in-hand with strengthening the WHO’s normative and technical capacities, including the Chief Scientist’s Office, the Health Emergencies Programme, and the WHO Academy, and with encouraging greater staff mobility and budget flexibility to bolster the WHO’s capacities at the country-level. In line with the Framework for Engagement with Non-State Actors (FENSA), leaders must enable more robust and transparent engagement with key stakeholders such as civil society and the private sector.
  • Strengthen the IHRs to foster more timely and accountable response to pandemic threats, including to authorize international investigations. Leaders should afford the WHO the ability to independently investigate potential and emerging threats, specify better information sharing, and better calibrate the definitions of a Public Health Emergency of International Concern (PHEIC). Metrics on equity, R&D, infection prevention control, capacity strengthening, and water, sanitation and hygiene should also be included in the IHR Monitoring and Evaluation Framework, to incentivize countries to assess, plan, prioritize, and better support sustainable and resilient health systems, and promote healthcare worker safety.
  • Support other voluntary and compulsory instruments to strengthen accountability of nation states and foster multilateral cooperation for pandemic preparedness and response. Many gains can be made by strengthening existing mechanisms and instruments, which should be prioritized alongside the proposal for a new pandemic treaty. Such instruments should promote accountability in functions including ensuring novel countermeasures are treated as global public goods; motivating faster flow of financing to address direct and collateral impacts of pandemics, including protecting frontline health workers and social protection for vulnerable populations such as refugees and those living in conflict-affected areas; reaffirming the centrality of human rights considerations in the context of a pandemic; boosting domestic R&D and manufacturing capacity; and establishing up data surveillance systems, and norms and standards around data sharing and data privacy.
  • Scale up national and global vaccine education efforts to increase vaccine confidence, distribution, and uptake. Countries should have budgets dedicated for vaccine education within health ministries, initiate public education campaigns to manage the spread of misinformation online, and build capacity for vaccine hesitancy research. Training should be prioritized for frontline healthcare workers, community leaders, and others in how to engage in difficult conversations on vaccine hesitancy.

6. Promote equity-focused initiatives and human rights protections in all aspects of pandemic preparedness, response, and recovery, including specific attention to address the intersectional and gendered effects of outbreaks.

World leaders should:

  • Commit to equitable financing to support populations most at risk for morbidity and mortality, including addressing inequities due to disparities in gender, race/ethnicity, sexual orientation, socioeconomic status, and disability.
  • Ensure commitments to human rights and equity are met, in alignment with IHR Article 3 on human rights, the United Nations Security Council Resolution 1325 for Women, Peace and Security, the UN Political Declaration for Universal Health Coverage, and the UN Sustainable Development Goals.
  • Commit to equal and diverse representation on emergency committees, including the IHR Emergency Committee and UN technical working groups, with active and meaningful participation of gender advisors and civil society groups as non-participant observers of EC meetings.
  • Ensure that all data pertinent to pandemic preparedness and response collected by the WHO and other health-focused UN bodies (as well as national governments) is published and disaggregated by sex and key socioeconomic groups.

 


 

An array of upcoming international summits — including the G20, G7, World Health Assembly, World Bank/IMF Meetings, and UN General Assembly — offer opportunities for leaders to act on this agenda. Critically, while health ministers have a key role to play, a concerted effort to end pandemics is a whole of government effort — and must be addressed at the level of heads of state. That is why the Pandemic Action Network supports the GPMB’s call for the UN Secretary-General to convene a focused UN High-Level Summit on Pandemic Preparedness and Response to mobilize increased domestic and international financing and advance efforts toward a new international framework for pandemic preparedness. Such a summit at head of state level should take up the forthcoming findings of the Independent Panel for Pandemic Preparedness and Response (the Independent Panel), the G20 High-Level Independent Panel for Financing the Global Commons (HLIP), the International Health Regulations (IHR) Review Committee, and the proposal for a new international treaty on pandemic preparedness and response.

World leaders must seize this opportunity to commit to action and leave a legacy of a healthier and safer world. We can pandemic-proof the future if world leaders act now. The world can’t afford to wait.

Recommendations for the Biden-Harris Administration – Now or Never: An Agenda for Global Action to Make America and the World Safer from Pandemic Threats

We urge President-elect Biden and the incoming Biden-Harris Administration to launch and lead an aggressive agenda for action on global health security to end the COVID-19 pandemic as quickly as possible while accelerating global preparedness for the next pandemic. The following five-point agenda for action has been prepared by a group of leading U.S. global health policy experts, including two of our Pandemic Action Network co-founders. The outlined recommendations reflect the group’s collective experience as well as the conclusions of an extensive body of research and reports from numerous expert groups over the past five years. 

As the pandemic has upended lives and livelihoods in every household in America and every corner of the globe, the political moment is ripe for President-elect Biden to galvanize and lead a global coalition of public and private actors around a shared commitment to help prevent a deadly and costly pandemic like COVID-19 from happening again. President-elect Biden has the opportunity to leave a longer-term legacy that will better prepare humanity to more effectively address emerging pandemic threats, and break the persistent cycle of panic and neglect once and for all. Waiting until this crisis is over or until the next one happens will be too late. It’s now or never. 

Read the five-point agenda white paper here: Now or Never: An Agenda for Global Action to Make America and the World Safer from Pandemic Threats

Break the Cycle of Panic and Neglect: Preventing the Next Pandemic

Time for unprecedented international cooperation say global health organizations

In the wake of the US decision to terminate the relationship with the World Health Organization (WHO), Pandemic Action Network and leading global health organizations have published a brief paper outlining some of the critical steps that the world needs to take to prevent pandemics.

The report sets out a key challenge for global leaders to work together in an unprecedented way to end COVID-19 as swiftly as possible and prepare for future pandemic threats.

The report, published jointly by the Pandemic Action Network, ONE, PATH, Nuclear Threat Initiative (NTI), Global Health Security Agenda Consortium (GHSAC), Management Sciences for Health (MSH) and Global Citizen highlights how years of ‘panic and neglect’ in the international health system has led to inadequate preparedness for pandemics in every country, resulting in the loss of hundreds of thousands of lives to COVID-19. Among the report’s recommendations is to strengthen WHO. Read the report HERE.